A Functional Medicine Approach to PCOS PCOS is complex but the right supplements can truly make a difference. When it comes to managing PCOS naturally, three supplements stand out for their science backed benefits: 1) Berberine often compared L Carnitine has become one of our top 5 sellers the last few years and when you review the research, you can see why. L carnitine is a supplement probably more well known if Acetyl l Carnitine Ameliorates Metabolic and Endocrine Alterations in Women with PCOS: A Double Blind Randomized Clinical Trial Advances in Therapy Springer Nature Link