Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst Enzymes of glycolysis and the pentose phosphate pathway as targets of oxidants: Role of redox reactions on the carbohydrate catabolism ScienceDirect Pentose phosphate pathway drives vascular maturation Nature Metabolism Role of glutathione cycle and the pentose phosphate pathway in the Download Scientific Diagram